Speakers - 2027

Title: TBI diagnostic and therapeutics

Abstract

Traumatic brain injury (TBI) remains a leading global cause of disability, and recent developments highlight a shift toward precision neurotrauma. Advances in blood biomarker testing, including GFAP and UCH-L1, are supporting earlier assessment of mild traumatic brain injury and helping clinicians make more informed decisions about the need for CT imaging.In critical care, treatment strategies for intracranial pressure management continue to evolve, while research is investigating whether combining intracranial pressure monitoring with brain oxygen monitoring can improve patient outcomes. Large research initiatives, including CENTER-TBI and TRACK-TBI, are helping researchers understand the biological and psychosocial differences among patients with brain injuries and develop more individualized approaches to treatment.The presentation will address the definition and classification of traumatic brain injury, common causes such as falls, vehicle accidents, sports injuries, and violence, and symptoms including headaches, confusion, memory difficulties, mood changes, and loss of consciousness. It will also cover diagnostic approaches, including physical examinations, CT and MRI imaging, and neuropsychological assessments.Treatment options may include rest, rehabilitation therapies, medication for symptom management, and surgery in severe cases. The presentation will also consider long-term cognitive, physical, and emotional effects and the importance of ongoing support.For mild traumatic brain injury, particular attention will be given to biomarker-guided triage, individualized monitoring, risk-stratified follow-up, and targeted rehabilitation interventions. Prevention strategies, including helmet use, seatbelts, and fall-proofing homes, will also be discussed.The lecture will emphasize early intervention and a multidisciplinary approach to care, highlighting how precision diagnostics and individualized treatment strategies may help improve recovery and long-term outcomes for people affected by traumatic brain injury.