Hemiplegic shoulder pain is a common and disabling complication following stroke, frequently leading to prolonged rehabilitation, reduced functional recovery, and decreased quality of life. Various conservative interventions have been proposed, yet optimal non-invasive pain management strategies remain uncertain. High-intensity laser therapy has emerged as a promising physical modality in neurorehabilitation; however, its clinical effectiveness in hemiplegic shoulder pain has not been comprehensively synthesized.
This presentation reports the findings of a systematic review and meta-analysis evaluating the effectiveness of high-intensity laser therapy in post-stroke patients with hemiplegic shoulder pain. A comprehensive search of PubMed, Scopus, Web of Science, Cochrane Library, and PEDro was conducted to identify randomized controlled trials published through December 2025. Studies comparing high-intensity laser therapy with conventional exercise or other physical therapy interventions were included.
Five randomized controlled trials involving 213 patients met the inclusion criteria. Meta-analysis demonstrated that high-intensity laser therapy significantly reduced shoulder pain intensity compared with control interventions. Additionally, meaningful improvements were observed in shoulder function and abduction range of motion. Sensitivity analyses confirmed the robustness of these findings after addressing heterogeneity.
The results highlight high-intensity laser therapy as an effective adjunctive intervention for managing hemiplegic shoulder pain in stroke rehabilitation. This presentation will discuss the clinical implications of these findings, potential mechanisms of action, and considerations for integrating high-intensity laser therapy into routine neurorehabilitation practice.
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